Bandages infused with casein – a protein present in cow’s milk and used as a weight-training supplement – can “considerably” speed up wound therapeutic processes in comparison with regular dressings, scientists have stated.
Researchers from College School London (UCL) discovered that wounds in diabetic rats healed extra rapidly once they had casein bandages on, in contrast with utilizing regular bandages or leaving the cuts untreated.
The staff stated its findings, revealed within the journal Royal Society Interface, elevate hope that casein, which is affordable and broadly out there, might change dearer supplies used in wound dressings such as silver.
Dr Jubair Ahmed, of UCL Mechanical Engineering, the primary creator on the research, stated: “Extra work is required to make sure that casein dressings are secure and efficient in people, however these preliminary findings are promising.
“Our objective is to do that on a mass scale, in order that the tip product might be as low cost as potential.”
Casein is discovered within the milk of all mammals however is extra ample in cow’s milk, the place it accounts for about 80% of the protein content material.
Till not too long ago, casein was discarded with out use however research recommend it may well enhance muscle progress and assist with restoration after train.
To make the casein bandages, the researchers blended pure casein with polycaprolactone (PCL), a sort of biodegradable plastic generally used for bandages.
The staff divided the rats with an identical pores and skin wounds into three teams: the primary was handled with casein bandages, the second was given regular bandages and the third didn’t obtain any remedy.
Dr Ahmed stated diabetic rats have been chosen as a result of they’re extra liable to having wounds, like people with diabetes.
Therapeutic progress was checked after three, seven, 10 and 14 days.
Dr Ahmed stated that after 14 days, the injuries handled with casein bandages “had solely 5.1% of the wound space left in comparison with with the untreated group, which was round 45.6%”.
Rats handled with regular PCL bandages had 31.1% of the wound space nonetheless left to heal after a fortnight.
Dr Ahmed stated: “We discovered that in comparison with no remedy in any respect, there was a major distinction between the wound closures (when casein bandages have been used).
“Even when in comparison with utilizing the fibres (bandages) with out casein, there was an enormous distinction in how a lot the injuries closed.”
Professor Mohan Edirisinghe, of UCL Mechanical Engineering, senior creator on the research, stated: “All of the analysis thus far means that casein has wound therapeutic potential, however in the meanwhile we don’t actually know why in any nice element.
“Casein has antimicrobial and anti inflammatory properties, which can actually play a component.
“The subsequent step might be to grasp the organic interactions going down earlier than we are able to take into account scientific trials in people.”